systemsbiology007

Eric Lindblom

General

System

Theory

Theoretical Biology:

---

Microtechnique Advanced Study

The orientation of this website is psychology. The point is to take a long look at Systems Biology and relate that to a little defined area in Psychology: Systems Psychology leading to a new paradigm: Psychological Reaction Networks (PRNs).

The PRN is a quantum transfer particle that describes the dynamism of acceleration and position between psychological objects at a systemic level. As that construction (PRN) develops, it may become clear!

Hypothesis: The PRN overturns the following assertion. "In its simplest form, it applies to the position and momentum of a single particle, and implies that if we continue increasing the accuracy with which one of these is measured, there will come a point at which the other must be measured with less accuracy. Mathematically, if Δx and Δp are the uncertainties in the measurements of the position and momentum, then the product ΔxΔp is at least on the order of Planck's constant."

http://en.wikipedia.org/wiki/Uncertainty_principle

Lindblom

Cognitive Science

Harvard University

For Harvard course, click:

http://h2o.law.harvard.edu/ViewProject.do?projectID=515 

http://en.wikipedia.org/wiki/Planck%27s_constant

---

What is Psychology in relationship to Biology?

"Psychology differs from biology and neuroscience in that it is primarily concerned with the interaction of mental processes and behavior on a systemic level, as opposed to studying the biological or neural processes themselves."

http://en.wikipedia.org/wiki/Psychology

---

Some Background:

There is an interface between Psychology and Biology (including information theory) that can be explored through General System Theory. Systems Biology attempts some of that interface. The new paradigm,  Psychological Reaction Networks (PRNs), explores some of the rest.

Herein, the paradigm shall explore the relationships between specific, general and unified theory.

Lindblom

Pro Re Nata

---

Deep Background:

"One of the theorists who can be seen as a precusor of systems biology is

Ludwig von Bertalanffy with his

general systems theory."

http://en.wikipedia.org/wiki/Systems_biology

"In 1952, the British neurophysiologists and nobel prize winners Alan Lloyd Hodgkin and Andrew Fielding Huxley constructed a mathematical explaining the action potential propagating along the axon of a neuronal cell.

In 1960, Denis Noble developed the first computer of a beating heart. The years 60s and 70s view the development of several approaches to study complex molecular systems, such as the Metabolic Control Analysis. The successes of molecular biology throughout the 80s, coupled with a skepticism toward theoretical biology, that then promised more than it achieved, caused the quantitative ling of biological processes to become a somehow minor field. However the birth of functional genomics in the 90s meant that large quantity of good quality data became available, while the computing power exploded, making possible more realistic s. In 1997, the group of Masaru Tomita published the first quantitative of the metabolism of a whole (hypothetical) cell. Around the year 2000, when Institute of Systems Biology were established in Seattle and Tokyo, Systems Biology emerged as a movement in its own right, spurred on by the completion of various genome projects, the large increase in data from the omics (e.g. genomics and proteomics) and the accompanying advances in high-throughput experiments and bioinformatics."

http://en.wikipedia.org/wiki/Systems_biology

"Systems biology is the study of an organism, viewed as an integrated and interacting network of genes, proteins and biochemical reactions which give rise to life. Instead of analyzing individual components or aspects of the organism, such as sugar metabolism or a cell nucleus, systems biologists focus on all the components and the interactions among them, all as part of one system. These interactions are ultimately responsible for an organism´s form and functions. "

http://www.systemsbiology.org/Intro_to_ISB_and_Systems_Biology/Systems_Biology_--_the_21st_Century_Science

The New Paradigm:

Systems Psychology

Lindblom: Psychological Reaction Networks (PRNs):

Please note that one goal of this website is to move toward Psychological Reaction Networks using techniques from Ludwig von Bertalanffy's unity of science concept as applied to Systems Biology.

So, how does a Psychological Reaction Network operate? It works like a Biological Reaction Network. That process is known. "The standard ing procedure is as follows: each candidate network (hypothesis) is translated into a set of ordinary differential equations with yet unknown parameters. Then an identification scheme is used that fits the unknown parameters in each set of differential equations to experimental data." Max-Planck-Gesellschaft, München

More?

Click:

http://www.mpi-magdeburg.mpg.de/research/projects/1002/1050

Lindblom

Please note the basic concept is from (General System Theory Squared (GST2).

Click for detail about GST2:

 http://h2o.law.harvard.edu/viewBoardThread.do?rootCommentId=3648

+